Amoxicillin and Clavulanate Potassium
Generic Name of
Amoxicillin and Clavulanate Potassium:
Amoxicillin and Clavulanate Potassium
Indications for
Amoxicillin and Clavulanate Potassium
Amoxicillin and Clavulanate Potassium tablets are normally used in dogs and cats for the treatment of persistent pyodermas, bone infections, infections in the mouth, pneumonia, and bladder infections as well as skin and soft tissue infections like wounds, abscesses, and dermatitis, caused by both gram positive and gram-negative aerobic and anaerobic microorganisms. Amoxicillin and Clavulanate Potassium are stable in the presence of gastric acid. It is bactericidal in action and possesses both the antibiotic properties of amoxicillin and the unique lactamase inhibiting effect of clavulanic acid, which makes it highly effective against Staphylococcus aureus, Streptococcus spp., E. coli, Pasteurella multocida, and Pasteurella spp., among others. However, it cannot be used for viral or parasitic infections.
Precautions when using
Amoxicillin and Clavulanate Potassium
Amoxicillin and Clavulanate Potassium is not recommended in animals with known hypersensitivity to penicillin or cephalosporins as this medication contains semi-synthetic penicillin. Drug administration is best done after food to avoid chances of stomach irritation and vomiting in dogs. In case vomiting persists, the veterinarian should be consulted. It is not advisable to use Amoxicillin and Clavulanate Potassium in pregnant or breeding animals as its safety has not been ascertained.
Side Effects of
Amoxicillin and Clavulanate Potassium
Amoxicillin and Clavulanate Potassium should be used only as per the directions of a licensed veterinarian. Though it is a safe and effective medication, it can cause side effects at least in some animals. Amoxicillin and Clavulanate Potassium could interact with other medications such as chloramphenicol and tetracycline. In some cases, animals might develop resistance and might not respond to treatment. Usage of Amoxicillin and Clavulanate Potassium might also result in diarrhea, which is caused by a change in the bacterial population in the animal’s intestine.
Dosage for
Amoxicillin and Clavulanate Potassium
Amoxicillin and Clavulanate Potassium are presented in tablet forms of various strengths of 62.5 to 400 mg, and a 50 mg/ml liquid oral suspension. The ideal dosage is 6.25 mg/lb (1 mL/10 lb) of body weight twice a day. Skin and soft-tissue infections should be treated for 5 to 7 day. If animals fail to respond to the treatment even after 3 days of treatment, stop the therapy and consult a veterinarian. Though some conditions like urinary infections may require longer treatment schedules, make sure that the treatment does not exceed 30 days.
Brand Names of
Amoxicillin and Clavulanate Potassium
Clavamox, Synulox, Clavaseptin