Never use Selegiline in animals that are allergic to it or administer the drug to pregnant or nursing animals. Do not use the medicine in dogs that have Cushing’s disease caused by some reason other than a pituitary tumor. Avoid prescribing Selegiline in combination with SSRI antidepressants (fluoxetine), tricyclic antidepressants (clomipramine), narcotics such as meperidine, ephedrine or other MAOIs, insulin, phenytoin, sulfonamides such as Albon and phenothiazines such as acepromazine. Selegiline is rarely administered to cats. The medicine should only be used after making a proper diagnosis of pituitary-based Cushing's disease. Selegiline is not recommended for adrenal gland-based Cushing's disease.