It is an exclusive topical application for the canine ear canals; never administer through any other route. Fluocinolone acetonide and Dimethyl Sulfoxide are not safe in pregnant animals as it might lead to miscarriage, fetal death, retained placenta, and metritis. If lacerations fail to heal, consult a licensed veterinarian for possible antimicrobial therapy and follow-up. Ensure that the medication does not enter the dog’s eyes; pet owners must wear protective gloves while applying the medication. Never exceed the prescribed dose as it might have serious adverse effects. Do not use Fluocinolone acetonide and Dimethyl Sulfoxide without the prescription of a licensed veterinarian, and thoroughly cleanse the pet’s ears before administering the medication.