This drug should not be given to cats or dogs that have a known sensitivity to antiplatelet drugs, or that have a difficulty forming blood clots on their own. This drug should not be given to pregnant, nursing, or breeding cats or dogs. Risk of excessive bleeding when used in conjunction with NSAID type drugs (rimadyl, aspirin, ibuprofen, naproxen). Use of Clopidogrel with the anticonvulsant phenytoin, or the diuretic torsemide, can affect the metabolism of the patient. Clopidogrel should not be taken in concert with other anticoagulants, like warfarin, due to risk of excessive bleeding and a change in metabolism.