Cart --
0 Items in Cart
Your Shopping Cart is Empty

K9 Advantix vs. Frontline Plus for Dogs

Comparing Frontline Plus and K9 Advantix for Dogs' Fleas and Ticks

By Kat Sherbo. November 08, 2012 | See Comments

  • expert or vet photo
    vet verified

    PetCareRx Staff Veterinarian

    DVM

K9 Advantix vs. Frontline Plus for Dogs

K9 Advantix and Frontline Plus for Dogs are some of the top flea and tick treatments--but how do you know which is better for your dog? Here are the key differences.

Biting pests like fleas and ticks can mean unwanted pain and discomfort for dogs, and some serious illnesses can result—some tick bites can lead to Lyme disease or other diseases, and fleas can carry tapeworm. 

Protecting your dog is a no-brainer, but how do you know which repellent will work best for your dog? 

You’ve probably been recommended Frontline Plus or K9 Advantix, or heard about one or both. Depending on what pests your dog is exposed to, how old your dog is, and what your dog’s lifestyle is like, one brand might be better suited to your pet than the other.

What types of pests does each brand protect against?

  • K9 Advantix kills fleas, ticks, mosquitoes and chewing lice and also repels ticks, fleas, biting flies, and mosquitoes. If you live in an area with lots of mosquitoes or flies, this may be the best choice.

  • Frontline Plus kills fleas, ticks, and chewing lice, and prevents fleas from laying new eggs.

How long does a dose last?

Both products last one month after application, and both are waterproof, so they’ll keep working if your dog goes swimming or needs a bath.

Should my dog be kept inside or alone after the dose?

  • After applying K9 Advantix, wait 48 hours before bathing your dog or letting it swim in a lake or pond—the medicine is dangerous to aquatic life.

  • K9 Advantix cannot be used on cats, and you should keep your dog away from any cats for 24 hours after applying the dose.

  • After applying Frontline Plus, don’t let your pet get wet until the product is dry, which usually takes 24 hours.

Are there any side effects?

Both products may cause some temporary skin irritation. If this persists or worsens after a few days, you should talk to a veterinarian.

My puppy is only a few weeks old. Can I still use K9 Advantix or Frontline Plus?

K9 Advantix can be used on dogs at least 7 weeks old, and Frontline Plus can be used on dogs at least 8 weeks old.

My dog is pregnant or nursing. Can I still use one of these medications?

  • Frontline Plus is approved for use on dogs that are pregnant, lactating, or breeding.

  • You should consult a veterinarian before using K9 Advantix on pregnant or nursing dogs.

How does it work?

  • Both products are topical medications, meaning you place the medicine on your dog’s skin. You’ll have to brush aside your dog’s hair and be sure the medicine is applied directly to the skin, to prevent it from coming off.

  • When applying Frontline Plus, apply the entire dose to one spot on your dog’s shoulder blades.

  • When applying K9 Advantix to a dog that weighs up to 20 pounds, apply the dose to 2 or 3 spots on your dog’s back from the shoulder blades to the base of the tail. If your dog is over 21 pounds, separate the dose into 4 to 6 spots along the back from the shoulder to the tail.

Having a dog that’s suffering from fleas and ticks can be stressful on you as well as uncomfortable and dangerous for your dog. Be sure to treat your pet for the pests in your area, and you’ll both be happier and healthier.

More on Fleas and Ticks

Flea and Tick Questions Answered
How do Dogs Get Fleas?
Get Rid of Fleas in 8 Steps - Infographic
My Dog Has Fleas, What Should I Do?
Are Flea and Tick Treatments Safe?
All Your Advantage II Questions Answered

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian with respect to your pet. It has, however, been verified by a licensed veterinarian for accuracy.

Was this article helpful?