PRN Pharmacal Proin (Phenylpropanolamine) http://cdn.petcarerx.com/img/PrdImg/095x095/10909_001_m.jpg Proin is a prescription, liver-flavored chewable tablet, intended to manage urinary incontinence in dogs, by constricting and strengthening the urinary sphincter. Proin is a supplemental adrenergic agent, which means it mimics adrenaline or epinephrine, w… Retail Price: 0.39 $ $0.26 In stock! Order now!
Proin (Phenylpropanolamine) 5 out of 5 based on 27 ratings.
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Proin (Phenylpropanolamine) 25mg Per Chewable Tablet
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Proin (Phenylpropanolamine) 25mg Per Chewable Tablet

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Prn Pharmacal Presents Proin (Phenylpropanolamine) 25mg Per Chewable Tablet. Proin is a Prescription, Liver-Flavored Chewable Tablet, Intended to Manage Urinary Incontinence in Dogs, by Constricting and Strengthening the Urinary Sphincter. Proin is a Supplemental Adrenergic Agent, which Means it Mimics Adrenaline or Epinephrine, which are the Hormones Needed to Trigger Vasoconstriction, the Constriction of Blood Vessels. Proin also Maintains Balanced Phenylpropanolamine Levels, Helping to Prevent the Negative Side Effects Associated with High Levels, Including Heightened Blood Pressure, and Hyperexciteability. Proin is a Classified Controlled Substance in Arkansas, Iowa, Louisiana and Oregon. [12147]


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About Proin (Phenylpropanolamine) 25mg Per Chewable Tablet
Proin is a prescription, liver-flavored chewable tablet, intended to manage urinary incontinence in dogs, by constricting and strengthening the urinary sphincter. Proin is a supplemental adrenergic agent, which means it mimics adrenaline or epinephrine, which are the hormones needed to trigger vasoconstriction, the constriction of blood vessels.

Proin also maintains balanced phenylpropanolamine levels, helping to prevent the negative side effects associated with high levels, including heightened blood pressure, and hyperexciteability. Proin is a classified controlled substance in Arkansas, Iowa, Louisiana and Oregon.
Key Benefits of Proin (Phenylpropanolamine)
  • Manages urinary incontinence in dogs
  • Helps to reduce accidents
  • Available in liver-flavored chewable tablets
Who's Proin (Phenylpropanolamine) For?
For dogs who have trouble controlling their bladder
Care Instructions
Store at room temperature away from moisture and heat.
Proin (Phenylpropanolamine) Specifications
Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.
Proin (Phenylpropanolamine) Ingredients
Phenylpropanolamine
Generic Alternatives to Proin (Phenylpropanolamine)
Phenylpropanolamine, Propalin
How Does Proin (Phenylpropanolamine) Work?
Proin uses Phenylpropanolamine, an adrenergic agent, to constrict and strengthen the bladder sphincter muscle, reducing leakage.
Side Effects and Warnings
Keep out of reach of children.

Do not give with ephedrine or epinephrine, or within two weeks of using a MAOi, such as Anipryl, selegiline or a Preventic Collar. Proin may cause restlessness and hyperactivity, pale gums, difficulty urinating, irritability, hypertension, and decreased appetite. Hypertension risk increases if Proin is given concurrently with non-steroidal anti-inflammatory drugs (NSAIDs), or with reserpine, tricyclic antidepressants, amitraz (the active ingredient of the Preventic tick control collar and canine Promeris, a flea control product), or ganglionic blocking agents. Conditions such as glaucoma, prostatic hypertrophy, hypertension, hyperthyroidism, diabetes mellitus, and cardiovascular disorders, may worsen.

Side effects may worsen if used in conjunction with other sympathomimetic drugs such as ephedrine or epinephrine. Notify your veterinarian of any medications, treatments or vitamins your dog is taking, prior to administering Proin.
Manufacturer PRN Pharmacal

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  • Prn Pharmacal Presents Proin (Phenylpropanolamine) 50mg Per Chewable Tablet. Proin is a Prescription, Liver-Flavored Chewable Tablet, Intended to Manage Urinary Incontinence in Dogs, by Constricting and Strengthening the Urinary Sphincter. Proin is a Supplemental Adrenergic Agent, which Means it Mimics Adrenaline or Epinephrine, which are the Hormones Needed to Trigger Vasoconstriction, the Constriction of Blood Vessels. Proin also Maintains Balanced Phenylpropanolamine Levels, Helping to Prevent the Negative Side Effects Associated with High Levels, Including Heightened Blood Pressure, and Hyperexciteability. Proin is a Classified Controlled Substance in Arkansas, Iowa, Louisiana and Oregon. [12148]

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Rated 4.8 out of 5 by 27 reviewers.
Rated 5 out of 5 by This has been a lifesaver I have a 12 year old Corgi that I rescued about a year and a half ago. She didn't have much use of her back legs when I got her. She also weighed about 40 pounds and had to be carried out to potty. Her muscles have further atrophied and she now can't even crawl(she used to be able to drag the back legs behind her#. After recurrent UTIs and her urine scalding her skin just from contact, the vet finally suggested this med. I remember when it was a prescription decongestant for humans but it was pulled from the market due to the same side effects that ephedrine had. It is a weight based medication, we started at one 25mg tab twice daily, but that didn't work. The dose is 0.91mg/lb twice daily. My vet increased my dog to 37.5mg#1 and a half of the 25mg tabs) twice daily and she can now hold it as long as you want her to. One piece of useful info, I found out the hard way: If my dog misses a dose, the flood gates will open up. If she misses a dose, she will have several accidents. My dog ,according to vet, isn't able to concentrate her urine so whaqt she drink just goes through her. As long as I don't miss a dose, she's good to go and can go morning, midafternoon, and evening. She sleeps on incontinence pads, the kind used in hospitals for people. This drug is a lifesaver for her. I don't mind cleaning her up as many times a day as necessary, but even if she only lays in urine for a few minutes before I clean her and change the pad, it causes her skin to get red and sore and her girl parts look like a strawberry they are so red. The med is worth every penny April 21, 2013
Rated 5 out of 5 by Preventing Accidents +++ After the usual test with the vet and a couple of months supply from the same vet, we had to find a better, cost effective source for this needed medication. As we are retired and low income, and everything else in life is high overhead, price is why we came to PET RX, receiving fast courteous service and quick shipping, and the price that works for us !!! December 11, 2012
Rated 5 out of 5 by Easy to use It works great for our 11 year old lab. She has been on it for 3 years and when she doesn't take it we know it within a few days. December 9, 2012
Rated 5 out of 5 Carpet saver My 5 Yr old GSD mix started leaking urine. After lab tests showed no infection or other issues her vet prescribed Proin. Great product! She is now leak free. Petrx is saving me almost 1/2 the cost if purchased through my veterinary office. October 28, 2012
Rated 5 out of 5 Great Product! My dog has leaked since we adopted her (at about 9 mos old). Vet put her on Proin to help her leaking. Within 24 hours her leaking had stopped and her anxiousness subsided. She used to leak when she slept and when she got really excited. After 3 years of being on the medicine, she has not leaked once! We give her half a pill (50 mg) twice daily. Vet said this is common in spaded female dogs. July 24, 2011
Rated 4 out of 5 Actually does help We have a 7 year old dobe that leaks on occasion. We started her on Proin about a year ago, and we have seen quite an improvement. It does take a while (a week or so) to start working, but keep at it. She has had a few times where she has leaked while on the medicine, but she has another health issue that might be contributing (going to a surgeon today for that). One thing I did notice shortly after she started taking the Proin was that she was so gassy!!! This did subside after some time. Our vet said this is not generally a side effect of Proin, but our dobe didn't smell that bad until after taking the pills. June 14, 2011
Rated 5 out of 5 For certian situations only My lab leaked when asleep ever since she was a puppy. She started on one pill, three times a day. Decreased her to now one twice a day for 14 years now, she's perfect. If we tried to take her off it she would immediately leak while she slept and her bed would have a wet spot. Start her up again on the Proin and back to perfect. It does happen more in female spayed dogs. It has to do with hormones. This is not for every leaking situation. January 29, 2011
Rated 5 out of 5 helps with effects of degenerative myelopathy I dont usually write reviews but i really believe in some cases this drug could save a dog's life. Once an elderly dog starts losing control of their bladder, most people will start thinking their time has come. This is a really hard thing to deal with especially with a big dog! My 14 yr old female german shepherd has DM and is losing feeling in the back end. She doesnt know she is going or if she does, its too late. On top of that, her difficulty in getting up and walking makes her not want to go out as often. We used a 3 pronged approach to deal with this: 1)Proin 2) rewards for going out and 3) a committment from everyone in the family to be sure she is taken out every few hours whether she asks or not. we realize we cannot rely on her judgment as to when its time to go out. She was having accidents once or twice a week. the drug took awhile to work but I honestly cant recall when the last time was. For now, its working and that has given us more quality time with her. August 10, 2010
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